Prevention of postmenopausal osteoporosis

Prevent and treat osteoporosis in postmenopausal 2009-04-13 11:15 main clinical manifestations of this disease are: waist, back, limb pain, weakness, severe activity limitation or bedridden; easy because of minor trauma induced fractures, can be found in diffuse bone tenderness; hump or significantly reduced figure or the occurrence of compression fractures.

biochemical indicators of serum osteocalcin (bgp) that osteocalcin synthesis by the osteoblasts, as an important indicator of bone formation; serum alkaline phosphatase (akp), the bone cells or the liver, the activity of two different cases in the normal liver function can be used as indicators of bone formation; and urinary calcium / creatinine (vca / cr) ratio, as indicators of bone resorption.

above target levels higher than normal, below normal or in the normal range, reflecting the bone remodeling cycle were shortened, extended or close to normal. postmenopausal bone osteoporosis is bone resorption exceeds bone formation disease.

nutritional factors of osteoporosis in postmenopausal women have an additional role in the occurrence of senile osteoporosis occurs to a certain extent.

calcium deficiency due to:

(1) absorption, the outdoor activities and receive less sunlight, vitamin d deficiency, 1,25 a (oh) 2vds decreased production in the kidney, affecting intestinal the absorption of calcium channel. In addition, the elderly less active, so that bone cells decreased, while the relative activity of osteoclasts increased bone resorption increased, becoming one of the factors of primary osteoporosis. (2) Long-term intake of calcium. domestic and foreign nutrition survey material shows that dietary calcium is generally lower than in the standard volume. older persons and reduce food intake, more a lack of calcium.

control of the main measures are:

(1) hormone replacement therapy.

the best selection of natural, short-acting, oral estrogen preparations. such as estradiol valerate, micronized estradiol 1-2 mg / day, estrogen o.625 mg / g, when the calcium intake amounted to 1,500 mg / g, can halve the amount of hormone. synthetic hormones commonly used in China nylestriol for estriol derivatives, oral administration of 2 mg / 2 weeks, ethinyl estradiol 0.005 mg / day medroxyprogesterone acetate 2 mg / day, alternating every other day to take. (2) a sufficient amount of calcium intake is the most basic method of prevention and treatment of osteoporosis.

In order to prevent bone loss in postmenopausal women, need calcium to 1,500 mg / day, women over the age of 65 should be increased to 2500 mg / day. In order to prevent bone loss in case of night fasting, should drink at every night before bed serving of milk or calcium.

summary, attention to nutrition, calcium supplement and strengthen the training, prevention and treatment of postmenopausal osteoporosis, the basic means of laser pro-replacement therapy also has the effect of holding special shall be carried out under the guidance of doctors.